Ron Lester was a Hollywood actor who became famous for playing Billy Bob, the 500-pound high school football player in the 1999 blockbuster movie, Varsity Blues. He also starred on the WB Television series, Popular. At age 30, after his massive obesity had caused him to have four arthroscopic knee surgeries and two “mild” heart attacks, he had gastric bypass surgery and eventually lost 349 pounds, going from 508 pounds down to 159 pounds. After that, he had 17 plastic surgeries to remove his excessively-stretched skin. In 2008, he was the keynote speaker at the ObesityHelp National Conference. In 2016, at the very young age of 45, he died of kidney, liver, heart and lung failure caused primarily by damage from his years of massive obesity.