The Over-the-Counter Cancer Cure You’re Not Supposed to Know About

Image result for The Over-the-Counter Cancer Cure You’re Not Supposed to Know About

Telomere-Cancer
Alex Pietrowski,
Waking Times

It’s no secret that cancer treatment has become its own thriving industry and the money to be made from prescribing cutting edge pharmaceuticals, chemotherapy and radiation treatment is immense. Profit is the paradigm for modern medicine, but as our knowledge of cancer continues to grow we continue to be reminded that many verifiably effective and affordable treatments for cancer exist, but seems to be unwanted or outright prohibited by the medical establishment.

Mebendazole (MBZ) is a commonly found, over-the-counter anti-parasite medication, used most often to rid the body of pinworms. It came into use in 1971, and now retails under a number of product names including Vermox, Ovex, Antiox, Combantrin and Pripsen. Found in most pharmacies and even available online, the drug is widely used, yet very few are aware of the effect it is seen to have in fighting cancerous tumors.
In the fight against cancer, the main attempt is to isolate then attack specific cells with poisons or by surgically removing body tissue. Radiation and chemotherapy are dangerous to the entire body, killing much more than just cancerous growths. MBZ, on the other hand is a unique treatment because it does not seek to kill cancerous cells with poisons, targeting instead the reproductive process of cells that have been replicating beyond their natural limit.

Known as micri-tubule inhibitors, this class of drugs prevents the replication of cells who’ve overgrown their capacity to reproduce correctly, which is the very nature of cancer.

Telomere“Human cells have a maximum number of times that they can reproduce themselves before the accumulated errors finally prevent reproduction — it’s called the Hayflick Limit. Most scientists agree that this number is around 60 times.

This “programmed” lifespan of a cell is determined by the length of a benign string of molecules attached to the ends of the DNA coils. Like leaders on a movie film, these break off or become misaligned during the replication process and provide a buffer zone, protecting the real DNA code. The longer a cell’s leader, called a telomere, the more it can reproduce and the longer an organism can live.” [Source]

First synthesized in the late 1960’s subsequent research has revealed more about the drug’s potency in stopping cancer cells without causing collateral damage. A 2014 study entitled, Repurposing Drugs in Oncology (ReDO)—mebendazole as an anti-cancer agent, concluded MBZ holds great promise in treating tumors, especially when used in combination with other existing cancer treatments.

“Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types…

READ: Why Oncologists Don’t Like Baking Soda Cancer Treatment

Based on the evidence presented, it is proposed that mebendazole would synergise with a range of other drugs, including existing chemotherapeutics, and that further exploration of the potential of mebendazole as an anti-cancer therapeutic is warranted.” [Source]

aken orally as a chewable tablet or in liquid form, the medicine has appeared in a number of cancer studies, including this study that looked at the effects of MBZ on cancerous tumors of the lungs:

“Oral administration of MZ in mice elicited a strong antitumor effect in a s.c. model and reduced lung colonies in experimentally induced lung metastasis without any toxicity when compared with paclitaxel-treated mice.” [Source]

Mebendazole-300×172

The last manufacturer of mebendazole in the United States was Teva pharmaceuticals who for unstated reasons discontinued the product in 2011, however, foreign-sourced brands are available for sale in pharmacies and at Amazon.com in the US. It is not yet recognized by the medical establishment as an anti-cancer drug, however, it many physicians are able to recommend its usage for reasons other than treating worms.Add mebendazole to the growing list of so-called ‘alternative’ cancer treatments which are affordable, effective, widely available, yet broadly ignored by the cancer industry.

Read more articles from Alex Pietrowski. About the Author

Alex Pietrowski is an artist and writer concerned with preserving good health and the basic freedom to enjoy a healthy lifestyle. He is a staff writer for WakingTimes.com and Offgrid Outpost, a provider of storable food and emergency kits. Alex is an avid student of Yoga and life.

Sources:

-http://viewzone.com/mebendazole.html
-https://en.wikipedia.org/wiki/Mebendazole
-http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096024/
-http://www.ncbi.nlm.nih.gov/pubmed/12479701
-http://neuro-oncology.oxfordjournals.org/content/early/2011/07/14/neuonc.nor077.full

A Promising New Drug Kills Pain Like Morphine—And It’s Not Addictive, Either

by Jordan E. Rosenfeld
Throw around the word “opioid”—a morphine-derived painkiller like heroin, Vicodin, or Oxycontin—and “epidemic” is likely to follow. The Centers for Disease Control estimates that U.S. deaths from opioid abuse are at a record high, with 78 fatalities occurring every day, a number that has quadrupled since 1999. A 2016 Kaiser Health survey found that nearly half of respondents reported knowing someone with an addiction to heroin, which in certain parts of the country is becoming a cheap, easily accessible alternative once the prescription runs out.

Congress has responded by authorizing $181 million in state grants for substance abuse treatment centers, while President Obama has made anti-addiction drugs more available. Yet the root cause remains largely unaddressed: People keep overdosing on opioids because they’re as incredibly effective—and dangerously addictive—as ever.

Image result for A Promising New Drug Kills Pain Like Morphine—And It’s Not Addictive, Either

But help appears to be on the way, thanks to scientists across four institutions—UC San Francisco, Stanford University, the University of North Carolina, and the Friedrich-Alexander University Erlangen-Nurnberg in Germany—who’ve developed a compound from scratch that kills pain just as effectively as opioids, though it has entirely different characteristics.
If you use opiates you get to kiss God. So your brain starts telling you to go do it again.

The four-year effort was funded by the U.S. National Institutes of Health. Rather than beginning as many studies on drug candidates do—by dissecting the molecular structure of a certain compound—the researchers began by looking at the brain. Specifically, the opioid receptor in the brain, which activates a signal in the dopamine circuit.

Brian Shoichet, PhD, a professor of pharmaceutical chemistry in UCSF’s School of Pharmacy and co-senior author on the paper, which was published last month in Nature, calls this “the happiness circuit, involved in a lot of types of addiction,” from nicotine to gambling and, yes, opioid addiction.

As described by Ivan Hodes of Alaska Commons:

The point of the signal is to make you remember that whatever you did felt good, so that you do it again the next time you have the opportunity. [When you take opioids, the] brain releases just gigantic amounts of dopamine, far more than are released by endorphins, and so you feel pleasure, euphoria, like you’ve never felt before (Lenny Bruce once described it as “like kissing God”).

Now your brain has learned something: If you use opiates you get to kiss God. So your brain starts telling you to go do it again, just begging you.

The key was to find a molecule that would bind well with that opioid receptor without affecting dopamine levels. Building on previous findings and using computational modeling, “We screened three trillion molecules, winnowed that down to twenty-three, and we went from there,” says Shoichet.

Eventually, the researchers were able to isolate a single molecule called PZM21.
There’s an American cultural phenomenon that goes with taking a pill, to have no symptoms at all and function at your highest level.

The chemical structure of this molecule is very different from opioids,” Shoichet says, and does not activate the dopamine circuit in mice, which the team tested for signs of addiction. Years later, those signs simply aren’t there. The mice didn’t experience a slowdown in breathing either, which is a major contributor to opioid-related deaths.

Like morphine, this molecule binds to the mu-opioid receptor,” Shoichet explains, but unlike morphine, PZM21 doesn’t activate the neural pathway that leads to side effects like depressed respiration and constipation.

The drug is a big step toward ending our national addiction to prescription narcotics, which likely kicked off in the late 1980s when a series of studies minimized the addictive nature of opioids right around the same time that organizations like the American Pain Society “campaigned to make pain what it called the ‘fifth vital sign’ that doctors should monitor, alongside blood pressure, temperature, heartbeat and breathing.”

Harold Jonas, PhD, LMHC, a Florida-based addiction counselor, and creator of an opioid recovery app called FlexDek MAT, believes the epidemic stems from what he sees as a uniquely American attitude, a “cultural phenomenon that goes with taking a pill, to have no symptoms at all and function at your highest level under the influence of different chemicals.”

PMZ21 is not a perfect painkiller, however, and it will be about a year or two before it goes into human clinical trials. While it relieves what Shoichet calls “conscious pain,” or the ongoing perception of pain, the drug does not affect “reflex pain,” which tells you to pull your hand away from a hot object before your brain actually registers your seared flesh. (Good news for the mice, at least: Placed on hot plates and dosed with PMZ21, they experienced as much pain relief as those on morphine without a dulled urge to jump off, according to Shoichet.)

Still, Shoichet says his team was “totally blown away by the results,” calling their discovery a “triumph of basic science.” Meanwhile, more progress is being made—another recent study published in the Nature journal Neuropsychopharmacology has found a brain mechanism that, if targeted by medication, could reduce one’s tolerance to morphine.

Source: health.good.is

When We Realized My Husband Has Autism

My husband Cj and I celebrated 10 years of being together. Ten years since we first met. We actually have three anniversaries (yep), but this one is the one I regard to be the most important because it was this one that marks the date that life as I knew it would be tipped upside-down.

Jessica Offer and her husband, CJ

God, my husband is gorgeous. He is the most incredible father who is ever-present for his tribe of girls. He has this cheeky grin, and he has a great sense of humor and makes me laugh a lot. He’s so bright. He teaches me lots of things. He also is fantastic at pulling me up when I’ve taken something too far, and he’ll often be the first person to roll his eyes and sigh with a comment like, “Why must you always insist on learning things the hard way?” (Because that’s me, baby, a bull in your china shop).

Next page

A Letter to Those Who Know Someone With Hypothyroidism

Hello friend, family member, work colleague or doctor of someone who lives with an underactive thyroid. You know someone very brave, very strong, battling a difficult disease called hypothyroidism.

group of friends with props sitting on floor

If you’re not a medical professional, you’re probably wondering what exactly an underactive thyroid is or what it does to someone who lives with it, so I’ll do my best to explain it as simply as possible.

You’ve likely already heard some things about it, for example that it causes weight gain and is an “excuse” people use for being overweight. In reality, hypothyroidism (another word for an underactive thyroid) does so much more to its host. It hurts when we see people use the term “thyroid problem” as code to describe someone who is overweight. It also belittles the condition.

Next page

To the Person Just Diagnosed With Ulcerative Colitis

So, you were just diagnosed with ulcerative colitis? Hey, I know what you’re feeling. I’ve been where you are right now. You might be young, maybe in your teens. You might be older, with children and grandchildren. Maybe it’s your child who’s been diagnosed with UC. Regardless of where you’re at we’ve all been there, all of us with UC, and it’s OK to be scared, shocked, indifferent or whatever you’re feeling right now. It’s all valid.

Image result for To the Person Just Diagnosed With Ulcerative Colitis

I would like to tell you a bit about my story from where I started my UC journey to where I am today because I want to share with you how it’s possible to have an amazing life with this chronic illness.

I was diagnosed when in December of 2008 when I was 15 years old. When I got diagnosed I felt, well, nothing, really. I felt kind of indifferent. I had gone to my school nurse with pain in my lower left side and I got an emergency appointment with the doctor since they suspected it might be the appendix. When that was quickly ruled out, the doctor kept asking me questions.

Next page

Meet the Breast Cancer Survivor Who Bared It All in John Legend’s New Music Video

You’ll see Legend’s wife, supermodel Chrissy Teigen, get ready to go out. You’ll see a boxer mid-workout. You’ll watch a bride shake off nerves, a girl get her ears pierced and a young woman try on clothes in a dressing room. You’ll see an elderly woman apply makeup, a teenager with Down syndrome look her outfit up and down, and a mom adjust her glasses. You’ll watch “Orange Is The New Black” actress and transgender advocate Laverne Cox take off her makeup and a cancer patient take off her wig.

And at the 2:43 mark, you’ll watch a woman take off her bra, revealing scars from the double mastectomy she had in 2010. Her name is Brenda O’Brien.

This is her story.

Brenda O’Brien in the music video of John Legend’s "You & I (Nobody in the World).”

Next page

What ‘I’m Tired’ Means to Someone With Hypothyroidism and Adrenal Fatigue

woman with her head down on her desk at work next to her laptop and several cups of coffee

Imagine this:

You go to bed at 8 p.m. because you’re so unbelievably tired. You sleep pretty much straight through the night, maybe waking briefly, but nothing to hugely disturb the amount of sleep you get, before your alarm goes off at 7 a.m. for work. That’s 11 hours of sleep. Yet you feel more tired than when you went to bed the night before. How is that possible? 

Next page

Ankylosing Spondylitis

What is ankylosing spondylitis?

Ankylosing Spondylitis (AS) is a type of chronic inflammatory arthritis that affects spine and the sacroiliac joints. Chronic inflammation in these areas causes pain and stiffness in and around the spine. AS affects men three times more often than women.The first symptoms of AS typically start in late adolescence. AS can cause inflammation or injury to other joints away from the spine, as well as to other organs, such as the eyes, heart, and lungs. AS can cause inflammation of the tendons surrounding the joints (enthesitis). Some of the common spots for enthesitis are the back of the heels (Achilles tendonitis), and underneath the bottoms of the feet (plantar fasciitis).

Next page

10 Great Things About Having Ulcerative Colitis

drawing of a woman with long waving blonde hair

Let me start by saying this: I know how much this disease can suck. I’ve felt so much of it myself, and I have dozens of friends who deal with inflammatory bowel disease (IBD) on a daily basis – often symptoms that are way worse than my own. And I know it does take time for a patient, especially a newly diagnosed one, to get to a place of peace with their body. I was diagnosed 16 years ago and still have days where I hate my insides and what they’ve put me through.

Still, I believe there are some benefits, some good things – even some blessings – that come with having ulcerative colitis. Once you’ve worked through the darkest days, you can slowly open your heart to the great things that happen even though you have a gut gremlin. For example…

Next page