THE CONSEQUENCES OF DELAY IN DIAGNOSIS OF FIBROMYALGIA IN PATIENTS

Results released from a national survey of U.S. women with fibromyalgia, illustrate the private and prolonged physical and emotional struggles patients with this condition face, underscored by delays in diagnosis, which a majority of respondents report as being one year or longer. As a result of fibromyalgia, two thirds (67%) of respondents say they are unable to keep up with household chores, nearly half (47%) report that their work life or career has been negatively affected, and two in five (42%) spend less quality time with their friends. Nearly one third (31%) say fibromyalgia has negatively affected their ability to experience intimacy.

Fibromyalgia is a condition marked by chronic, widespread pain and tenderness, and decreased physical function. It affects six to 12 million Americans, mostly women, three-quarters of whom are estimated to be undiagnosed. Results of the 48-state, 508-person survey were released by HealthyWomen.org, the nation’s leading independent source of health information for women. The survey was sponsored by Forest Laboratories, Inc.

“Fibromyalgia is a common medical condition affecting women,” said Elizabeth Battaglino Cahill, Executive Director of HealthyWomen.org and a registered nurse. “It is estimated that there could be as many American women living with fibromyalgia as there are living with diabetes. And while increased awareness has dramatically improved care for patients with this condition, we still have a lot of work to do to ensure patients have the support they need to live their lives fully.”

Remarkably, one in four (23%) respondents report having suffered for at least five years before receiving a diagnosis for their condition. Most respondents (71%) say they waited until they could no longer tolerate their symptoms before seeking a diagnosis. Examples of perceived barriers to a proper diagnosis include patients’ own lack of knowledge about the condition and physicians not recognizing symptoms.

Although fibromyalgia is a chronic disorder, a majority of respondents say they fear skepticism about their condition, with 64% expressing concern about being taken seriously, and 79% indicating the top quality they seek in a healthcare professional is assurance that their condition is being taken seriously.

“This survey quantifies what patients and their supporters have known and experienced that stigma, skepticism, lack of knowledge about fibromyalgia, and delays in diagnosis contribute negatively to patient outcomes.” added Battaglino Cahill. “However, with more knowledge, patients are overcoming these barriers to improving their lives, and that is an important lesson we can take away from this survey.”

Early diagnosis is important

Respondents whose diagnosis was delayed were more likely to report severe symptoms (68%) at the time of diagnosis, compared to those who were diagnosed within a year (42%). Patients diagnosed within a year are also significantly less likely to experience daily challenges in management of their households, relationships and careers.

“An earlier diagnosis is important,” said David Edelberg, M.D., founder of WholeHealth Chicago and a physician specializing in fibromyalgia treatment. “The sooner patients are diagnosed, the sooner they can begin an effective management plan and get back to their daily activities. This is why it’s critical for both doctors and patients to communicate effectively and for patients to not wait until they can no longer bear their symptoms before seeking help.”

Effective treatment and support from loved ones are critical

Since being treated, 51% of patients believe that their overall day-to-day life has improved. In addition, a greater number of patients who received more support from their spouse report that their day-to-day life has improved due to treatment (56%), compared to those who received the same amount of or less support (47%) since being treated.

Respondents say the following types of treatment have improved their symptoms:

— Prescription drug therapy (58%)

— Exercise (46%)

— Alternative therapies (43%), such as massage, meditation, acupuncture and chiropractic care

Unfortunately, many patients do not receive the support from friends and loved ones that they need:

— Of the 43% of respondents who say they rely most often on their spouse or significant other for support, only about a quarter (27%) say this person fully understands how fibromyalgia affects them
— After learning about their diagnosis, less than half of respondents say their friends (28%), children (33%) and spouses (43%) offered more support

“Arriving at an earlier and accurate diagnosis is only the first step for patients with fibromyalgia,” said Battaglino Cahill. “Women need to work closely with their physicians to find an effective treatment plan, and friends and loved ones must do their part to provide the ongoing encouragement that is critical to a patient’s improvement.”

About the survey

The survey, known as WE FEEL (Women Expressing Fibromyalgia’s Effects on their Everyday Lives), was designed to gather data and better understand perspectives on diagnosis and treatment, the relationship between fibromyalgia patients and their physicians, the impact of the condition on patients’ daily activities, and the types of support patients need and receive.

Research for WE FEEL was conducted by Edelman StrategyOne, using the field services of Harris Interactive Service Bureau. The 20-minute survey was fielded between May 5 and May 11, 2010. The findings are nationally representative of diagnosed, female fibromyalgia sufferers in the US. The total sample of 508 yields a margin of error of ±4.4% at the 95% confidence level, which means that 95 out of 100 times that a sample of this size is drawn, the results will not vary by more than 4.4 percentage points in either direction. The statistical significance is reported at the 95% level.

Source: HealthyWomen

Do You Lose Strength in the Hands Due to Fibromyalgia Rheumatic Diseases Yes?

Common feature that most fibromyalgia patients have is diffuse pain that affects a large part of the body. This disconcerting symptom is often accompanied by morning articular stiffness,Paresthesias in the hands and feet, ie tingling and numbness, sleep disturbances and above all a feeling of tiredness and fatigue that accompanies them throughout the day. This tiredness contributes to Fibromyalgia Rheumatic Diseases have a poor tolerance to stress affecting up to 90% of patients.This is why a study carried out by a team of the University of Granada, and published in January 2011 in the journal Archives of Physical Medicine and Rehabilitation, analyzed the resistance that these patients present in the hand, to be able to use it as a complementary tool In assessing the severity of Fibromyalgia Rheumatic Diseases in women.

The objective was to determine the strength of the strength test in the hand, in discriminating between the presence and absence of Fibromyalgia Rheumatic Diseases and the severity of the same in 81 women with the disease and 44 healthy women.They measured the resistance of the force in the hand with a maximum isometric force test, with the aid of a hand dynamometer. The women were classified according to the score obtained in: Moderate fibromyalgia (<70) and severe fibromyalgia (70 or more). The results observed were:The strength threshold in the hand that best discriminates between the presence and absence of fibromyalgia was 23.1 kg.The threshold that best discriminates between severe and moderate fibromyalgia was 16.9 kg.

A strength of the hand force of 23.1 kg or less was associated with a 33.8-fold higher probability of having Fibromyalgia Rheumatic Diseases after age delimitation.In the fibromyalgia group, a strength of the hand force of 16.9 kg or less was associated with a 5.3-fold higher probability of suffering from severe fibromyalgia.The conclusions of these investigators are: that resistance of the force in the hand is reduced in women with Fibromyalgia Rheumatic Diseases, as well as in those with severe fibromyalgia compared to their partners with moderate Fibromyalgia Rheumatic Diseases.They also point out that those women who do not comply with these proposed standards can guide the doctor to make a good diagnosis, as it would be used as a useful and informative tool.

Have you noticed that you have less strength and strength in your hands than your friends / family? In what aspects of daily life do you think a handicap?We hope that you share your impressions with us, that we will get to our network members.

7 Proven Black Seed Oil Benefits & Cures

Of the 630 scientific peer-reviewed articles that have been published about black seed oil benefits, one fact is clear: there are few issues that it cannot help the body overcome. With virtually no side effects, the healing prowess of black seed is actually quite unbelievable and it boggles the mind that most Americans have never heard of it!

Unique Black Seed Oil Benefits

The uniqueness of the seeds from southwest Asia Nigella sativa is first realized by the many names that it is referred to: (1)

Black cumin

Black caraway

Black sesame

Onion seed

Roman coriander 

“Black seed” is actually more of a description than a proper name, yet is preferred because it helps to distinguish it from caraway and cumin. Many health experts claim that it is, indeed, a true panacea; able to help cure everything from allergies to hypertension. Quite possibly, the most promising research has been done connecting Nigella sativa to multi-drug resistant bacteria. This is a real big deal because these so-called “superbugs” are becoming a significant public health risk. According to the National Institute of Health: (2)

  • Strains of bacteria and viruses that are antimicrobial-resistant are becoming virtually impossible to treat; including HIV, staphylococcal, tuberculosis, influenza, gonorrhea, candida, and malaria.
  • Between 5 – 10% of all hospital patients develop an infection from superbugs.
  • More than 90,000 of these patients die every year, up from 13,300 patient deaths in 1992.
  • People infected with superbugs typically have longer hospital stays, require more complicated treatment and don’t recover as well.

A study conducted by Jawaharlal Nehru Medical College researchers set out to determine just how potent black seed oil against some of these superbugs and pared it against several antibiotics such as Amoxicillin, Gatifloxacin and Tetracycline. According to the study,

“Out of 144 strains tested, most of which were resistant to a number of antibiotics, 97 were inhibited by the oil of black cumin!”

Next to oil of oregano, few things on the planet can boast this type of potency to microbes! The study uncovered that it was especially effective against multidrug resistant strains of P. aeruginosa and S. aureus.

The key to understanding why black seed oils benefits the body in this way is because it is rich in 3 key natural chemicals: thymoquinone (TQ), thymohydroquinone (THQ) and thymol.

The Power Behind Black Seed Oil Benefits: Phytochemicals

In an effort to offer a solution to the growing antifungal resistant problem people have with yeasts and molds, a recent study was conducted with the purpose of determining if Nigella sativa seed oil could help. Published in the Egyptian Journal of Biochemistry & Molecular Biology, scientists tested thymol, TQ and THQ against 30 human pathogens and were surprised to discover that: (3)

Each compound showed 100% inhibition for the thirty pathogens evaluated.

Thymoquinone was the best antifungal compound against all of the tested dermatophytes and yeasts, followed by thymohydroquinone and thymol.

Thymol was the best antifungal against molds followed by TQ and THQ.

What this study tells us is that Nigella sativa oil carries a very unique chemical constituency that is not only effective individually, but more importantly also collectively. Essentially proving that fungus and molds cannot exist in the presence of these phytochemicals, it is no wonder why researchers are seeking to solve the superbug problem with the mighty black seed!

Thymoquinone – An active ingredient in black seed, researchers have been investigating TQ since the 1960s. It is well known for its anti-oxidant, anti-inflammatory and anticancer properties that have been reported to help with encephalomyelitis, diabetes, asthma and carcinogenesis. (4) Interestingly, thymoquinone acts as a free radical or an effective superoxide radical scavenger, in addition to preserving antioxidant enzymes glutathione peroxidase and glutathione-S-transferase. Both Glutathione peroxidase and S-transferase are heralded for being major detoxifiers and greatly aid in cellular antioxidant defense systems because they protect the liver from toxins. (4,5)

Thymohydroquinone – A kin to thymoqinone, thymohydroquinone is one of the most potent natural acetylcholinesterase (AChE) inhibitors on the planet. (6) AChE inhibitors are chemicals that stop enzyme activity, which increases the amount of time and the amount of the neurotransmitter acetylecholine remains active in the brain. To give you an idea of their usefulness, pharmaceutical-grade acetylcholinesterase inhibitors are used medicinally to treat a wide range of conditions including: (7)

Apathy

Alzheimer’s disease

Autism

Glaucoma

Dementia

Myasthenia gravis

Neurodegenerative conditions

Postural Tachycardia Syndrome

Schizophrenia

Parkinson’s disease

Considering that the pharmaceutical approach to these diseases comes at a great cost to the patient, it offers much hope to literally millions to learn that safe, plant-based solutions are a viable alternative!

Thymol – The active ingredient that gives thyme essential oil its medicinal properties, thymol is a natural monoterpene that holds a number of useful qualities. For example, (8) (9)

It is commonly used as a tuberculocide and virucides to kill TB and various viruses.

It is used as a medical and general-purpose disinfectant.

It is a rapidly degrading, non-persisting pesticide.

It is also used in food flavorings, perfumes, mouthwashes, and even cosmetics.

According to the Environmental Protection Agency (9)

Thymol is among those pesticides for which EPA believes a broadly reduced set of generic data requirements is appropriate for reregistration. The Agency, therefore, has waived most generic data requirements for thymol with the exception of studies that are considered essential, including additional information about chemical purity, and product chemistry studies.

Top 7 Black Seed Oil Benefits

Of the many ways that black seed oil benefits the body, the 6 that stick out in the scientific literature its ability to help prevent cancer, diabetes, obesity, hair loss, skin disorders and infections like MRSA.

1. Cancer

Croatian scientists evaluated the antitumor activity of thymoquinone and thymohydroquinone in mice and discovered that the two phytochemicals in black seed oil can resulted in 52% decrease in tumor cells! (10)

Being rich in both chemicals, black seed is unique in that it can help prevent and treat cancer through a variety of mechanisms:

Anti-proliferation

Apoptosis induction

Cell cycle arrest

Reactive oxygen species generation

Anti-metastasis

Anti-angiogenesis

According to one study,

“The anti-tumor effects of thymoquinone have also been investigated in tumor xenograft mice models for colon, prostate, pancreatic and lung cancer. The combination of thymoquinone and conventional chemotherapeutic drugs could produce greater therapeutic effect as well as reduce the toxicity of the latter.” (11)

2. Liver Health

The liver is one of the most important organs in the body. Nearly every toxin gets processed through the liver, and the bile from the liver is the key to digesting fats and keeping your mind and body happy and healthy. For those that have struggled with poor liver function due to medication side effects, alcohol consumption, or disease, black seed oil could greatly speed the healing process. In a recent study scientists discovered that black seed oil benefits the function of the liver and helps prevent both damage and disease. (12)

3. Diabetes

Explained in a recent article published by the Journal of Endocrinology and Metabolism, researchers from the Indian Council of Medical Research highlight that black seed oil “causes gradual partial regeneration of pancreatic beta-cells, increases the lowered serum insulin concentrations and decreases the elevated serum glucose.” (13) This is actually quite profound because Nigella sativa is one of the few substances on the planet that is suggested to help prevent both type 1 and type 2 diabetes.

In fact, according to the study, black seed “improves glucose tolerance as efficiently as metformin; yet it has not shown significant adverse effects and has very low toxicity!” (13) This is HUGE because metformin, one of the most commonly prescribed type 2 diabetes drugs, can cause a wide slew of side effects including: (14)

Bloating

Constipation/Diarrhea

Flushing of the skin

Gas/Indigestion

Heartburn

Headache

Nail changes

Metallic taste in mouth

Muscle pain

Stomach pain

4. Weight Loss

The Journal of Diabetes and Metabolic Disorders published a study last June systemically reviewing the literature for plants that have anti-obesity properties and discovered that black seed oil was amongst the most effective natural remedies on the planet. (15)

Not traditionally believed to treat obesity, Nigella sativa is a marvelous anti-inflammatory agent that is known to help people lose weight in the same way that it helps diabetics. Specifically, by decreasing these weight gain triggers, black seed oil has helped millions shed excess weight: (16)

Appetite

Glucose absorption in the intestine

Liver gluconeogenesis

Blood glucose levels

Cholesterol

Triglycerides

5. Hair

Probably one of the most unique black seed oil benefits is its uncanny ability to help restore hair loss. No one quite understands why it happens, but it’s not too hard to guess that it has something to do with its powerful antioxidant and antimicrobial properties. By strengthening hair follicles, there is very good reason to see how black seed oil can help promote strengthened hair roots.

6. Skin

Produced in the retina, choroid and epidermis, melanin are pigments that protect the skin from damage. You probably are most family with it being the main chemical responsible for giving our eyes and skin their individual color. Known to promote and inhibit melanogenesis (melanin production), black seed oil benefits on the skin and other cells are profoundly healing. (17, 18)

For example, in a recent study conducted by Iranian researchers, Nigella saliva was found as effective as the  skin cream Betamethasone in improving quality of life and decreasing severity of hand eczema. (19) When you consider that black seed oil has virtually no side effects, the benefits of Nigella, in fact, far exceed medical intervention!

7. Infections (MRSA)

Of all the superbugs that black seed oil can kill, Methicillin resistant Staphylococcus aureus (MRSA) is one of the most important. MRSA is plaguing hospitals and nursing homes across the globe because ordinary staph infections are becoming resistant to generic antibiotics. The elderly population is especially at risk because it is generally associated with invasive procedures such as surgeries, intravenous tubing, and artificial joints. (20) Primarily due to weakened immunity, the growing population of senior citizens has made MRSA a global public health risk.

Thankfully, one of the strongest black seed oil benefits comes to the rescue.  Pakistan scientists took several strains of MRSA and discovered that each one was sensitive to N. Sativa, proving that black seed oil can help slow down or stop MRSA from spreading out of control. (21)

SOURCE : www.draxe.com

Before he hanged himself, a 13-year-old wrote this letter. His parents only want that his story be told.

Daniel Joseph Fitzpatrick was just a few weeks shy of his 14th birthday when he took his own life. His 17-year-old sister, Kristen, found him on August 11, hanged with his own belt. His parents, Maureen and Daniel Sr. , were overwhelmed with grief but they didn’t want to let that stop them from sharing his important and heartbreaking story. Daniel had been relentlessly bullied until he saw no other way out.

The teen wrote a multi-paged suicide note that his parents decided to publish. He describes how his sixth grade schoolmates and former friends at his Catholic school suddenly turned against him and how he had been subjected to daily bullying attacks:

“… Anthony took it all out on me. He bullied me along with John, Marco, Jose, and Jack they did it constantly until I went into a fight with Anthony everyone stopped except John he was angry… I ended up fighting John and got a fractured pinkie,” Daniel, also known as Danny, wrote that they teased him because of his weight, his grades, because he wasn’t as “tough” as the other boys. “I gave up.

The teachers either didn’t do ANYTHING.”

 

“My son’s story is now out there for the world to see and for the world to know the pain that he went through,” said Daniel’s father in a voice hoarse with emotion in an 18-minute video he posted on Facebook. “No child should have to go through what my son went through.” In the poignant recording, the mechanic also explained the he and his wife didn’t feel the school treated their concerns seriously when they took Danny’s troubles to the principal. “All I got was and all HE got was, ‘He’ll be fine. Is he in counselling? You have to try harder, Danny. These things will pass.’”

Daniel Sr. also had strong words for the parents of the boys Danny named in his suicide note: “You get to hold your children every night and every day for the rest of your lives and their natural lives.

I don’t get that anymore. Your little monsters took that from me. And my wife. And his sisters. Danny was a kind, gentle little soul. He didn’t have a mean bone in his body… I just want to hear him say, ‘good morning, dad’ one more time and that way I could tell him ‘good morning’ and ‘I love you,’ which I did every every day.”

SOURCE

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Image result for Before he hanged himself, a 13-year-old wrote this letter. His parents only want that his story be told.

4 Horrifying Reasons Why Not To Shave Your PUBIC Hairs Again (MUST see)

Many ladies are terrified their Vparta would possibly one way or the other cease working if they do not shave it, or their man will likely be fully turned off.

#1 The Shaving Fear
Many ladies are terrified their Vparta would possibly one way or the other cease working if they do not shave it, or their man will likely be fully turned off. First, a person will ALWAYS wish to have intercourse any time it doesn’t matter what it seems like down there. Second, it nonetheless works girls don’t be concerned!

#2 The Cuts

There are such a lot of angles and shapes you have to information your razor round down there, making it almost unimaginable to not minimize your self at the least as soon as! Most ladies additionally get extraordinarily painful rashes, even when they make it by way of the trenches with out nicking themselves.
#3 Protection
You could not understand, however the Vparta is extraordinarily delicate and is susceptible to being contaminated very simply. This is the reason your pubes are there, to PROTECT your treasured purse. Micro organism simply loves an open space to infiltrate.

#4 Stay Safe Ladies

The scariest one among all is that you’ve a a lot increased threat of catching a illness from a sensual accomplice. Your pubes can shield you from molluscum contagiosum, genital warts, and even herpes.

SOURCE : www.top15.me

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YOUR WIFE HAS FIBROMYALGIA? HERE ARE 25 WAYS TO SUPPORT HER

If your loved one has fibromyalgia, it is difficult to understand exactly what they were going through unless you’ve experienced it by yourself. They likely require much more time sleeping or resting than you and may not feel up to going out very often. Fibromyalgia can also inhibit a person’s ability to work, accomplish household works or even do everyday things such as showering and eating.

If you have a supportive spouse or significant other it makes all the difference. It’s not that we have pain and are exhausted. It changes your life. You are no longer the same physically or mentally ( my anxiety) so many things are gone. I know everyone feels the same way.

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If one person is chronically ill but the other is healthy, this can easily put strain on even the strongest of relationships. Although it may be harder to put yourself in the other’s shoes or find a balance in which you both feel like equal partners in the relationship, it is certainly not impossible – and for many couples, facing obstacles together such as chronic illness can actually strengthen their bond and deepen their love for one another.

We asked our community “Living With Fibromyalgia and Chronic Illness” and “Living With Fibromyalgia” to share ways for people to help their spouse or partner with fibromyalgia. If your loved one is affected by a chronic health condition like fibromyalgia, CFs, perhaps the following ways can help you better understand what they experience and provide some ideas of things you could do that might mean the world to them.

Here’s what our community told us:

1. When they are having a breakdown, hold them, let them cry and know you are there for them.

2. Learn as much as you can about it. Be patient. You might not understand what it’s like but bring empathetic and listening to your partner or spouse is so important. Unconditional love.

3. Ask your partner to listen to you, and to read from people who also have fibromyalgia.

4. Avoid making them feel guilty. Give reassurance and love. Lie in bed and hold them, tell them you’re in it for the long haul. And mean it!

5. Believe them first, be supportive second, be kind at all times third and pull your weight in the relationship in a practical way. They didn’t plan this any more than you did and you’re both in this thing together so help both of you to make the most of the journey. The more support they have the sooner they will find their own level of fitness and health but it takes quite some time and you will need to stand by them and lessen their physical and emotional load as much as you possibly can.

6. Show Love and Dont ask too many question in a flare up times

7. Draw them a nice warm bath,wash their hair,help them out,dry and brush their hair. Then just listening would be nice.

8. Be understanding, patient, share the household chores, be supportive when others question the veracity of illness, remember that this illness is no one’s fault or punishment to you. Above all, never stop loving the afflicted person.

9. Do exactly what you would want your love one to do for you if the roles were reversed.
Above all, be kind, loving, patient and funny

10. No guilt, a lil sympathy and self maintenance. Sometimes I can only take care of myself…make dinner once a week. Vac or clean a shower. Remember we can’t pick up things the same, or I can’t, ten lbs and I’m all but wore out

11. Not just hear what they are saying but actually listen!

12. Ask often about different aspects of pain, bring them small things that help-ice packs, meds, drinks, heating pad….lay with them tell them how much u want to take it away. Understand their struggles, do research

13. Fill in the gaps.. different forms of support where there are deficiencies. It is deep express expectations so they are known and understood then understand how it may be impossible to achieve. Be creative. Help with the pain or needing sleep on the weekends, but I do want to clean, beach comb, look for sea glass, Kayak yet it is limited, play volleyball (cannot anymore) Personally I believe movement is necessary to recover until the tingling in my lower legs begin starting the pain. If it feels like a shin splint i pushed because it felt great. I am painting the trim and windows which would take a normal healthy person one summer. It is going to take me two. I am ok with it. This is an example of lowered expectations yet helping me achieve goals which builds my esteem and strength.

14. Never say you are lazy

15. Never cut them down for not feeling good or not being able to do the things they once could do. Be supportive even if you don’t understand it all.

16. Keep them out of stressful situations. Allow them to rest when they need it.
If possible live somewhere the barometric pressure does not change too much- ewh the pain!

17. There’s a wonderful book called Fibromyalgia for dummies. My son read it I don’t know how many times. He really wanted to understand and help. My husband on the other hand left within a month.

18. When I say I can feel the energy being drained out of me like a needle taking blood please let me rest because the sweats flu pain and brain fog are just around the corner.

19. Make sure they understand that although they cannot function as before they are still a valued member of the family and that they are not a burden.

20. Ask your spouse what they would like from you and let them know that you want to help in any way you can. Every little favor or assistance makes a difference for me, but we’re all different. Some prefer as much independence as possible. Many prefer to be asked before automatically assuming what’s wanted or needed. Offer to help or do things to help around house without asking after you know what’s wanted and needed. Some of us feel guilty for putting the burden on others.

Reassuring your spouse that you’re there for them and don’t mind helping can and want to support and understand as best as possible can be a tremendous relief for your spouse. I personally only like my feet massaged with lotion. Other areas are too sensitive for massage. I need help around the house, with shopping etc. I need peaceful environment to rest.

What would help your spouse? What would help your spouse feel -a little better or more comfortable. Know you can’t fix or change the illness, but you can offer assistance and comfort. Too often people offer unsolicited advice and that can make things worse, putting more unrealistic expectations and pressure on me. Then I can become more depressed or feel unnecessary guilt and shame.
Hope this helps. 💜

SOURCE : www.fibromyalgiaresources.com

The Over-the-Counter Cancer Cure You’re Not Supposed to Know About

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Telomere-Cancer
Alex Pietrowski,
Waking Times

It’s no secret that cancer treatment has become its own thriving industry and the money to be made from prescribing cutting edge pharmaceuticals, chemotherapy and radiation treatment is immense. Profit is the paradigm for modern medicine, but as our knowledge of cancer continues to grow we continue to be reminded that many verifiably effective and affordable treatments for cancer exist, but seems to be unwanted or outright prohibited by the medical establishment.

Mebendazole (MBZ) is a commonly found, over-the-counter anti-parasite medication, used most often to rid the body of pinworms. It came into use in 1971, and now retails under a number of product names including Vermox, Ovex, Antiox, Combantrin and Pripsen. Found in most pharmacies and even available online, the drug is widely used, yet very few are aware of the effect it is seen to have in fighting cancerous tumors.
In the fight against cancer, the main attempt is to isolate then attack specific cells with poisons or by surgically removing body tissue. Radiation and chemotherapy are dangerous to the entire body, killing much more than just cancerous growths. MBZ, on the other hand is a unique treatment because it does not seek to kill cancerous cells with poisons, targeting instead the reproductive process of cells that have been replicating beyond their natural limit.

Known as micri-tubule inhibitors, this class of drugs prevents the replication of cells who’ve overgrown their capacity to reproduce correctly, which is the very nature of cancer.

Telomere“Human cells have a maximum number of times that they can reproduce themselves before the accumulated errors finally prevent reproduction — it’s called the Hayflick Limit. Most scientists agree that this number is around 60 times.

This “programmed” lifespan of a cell is determined by the length of a benign string of molecules attached to the ends of the DNA coils. Like leaders on a movie film, these break off or become misaligned during the replication process and provide a buffer zone, protecting the real DNA code. The longer a cell’s leader, called a telomere, the more it can reproduce and the longer an organism can live.” [Source]

First synthesized in the late 1960’s subsequent research has revealed more about the drug’s potency in stopping cancer cells without causing collateral damage. A 2014 study entitled, Repurposing Drugs in Oncology (ReDO)—mebendazole as an anti-cancer agent, concluded MBZ holds great promise in treating tumors, especially when used in combination with other existing cancer treatments.

“Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types…

READ: Why Oncologists Don’t Like Baking Soda Cancer Treatment

Based on the evidence presented, it is proposed that mebendazole would synergise with a range of other drugs, including existing chemotherapeutics, and that further exploration of the potential of mebendazole as an anti-cancer therapeutic is warranted.” [Source]

aken orally as a chewable tablet or in liquid form, the medicine has appeared in a number of cancer studies, including this study that looked at the effects of MBZ on cancerous tumors of the lungs:

“Oral administration of MZ in mice elicited a strong antitumor effect in a s.c. model and reduced lung colonies in experimentally induced lung metastasis without any toxicity when compared with paclitaxel-treated mice.” [Source]

Mebendazole-300×172

The last manufacturer of mebendazole in the United States was Teva pharmaceuticals who for unstated reasons discontinued the product in 2011, however, foreign-sourced brands are available for sale in pharmacies and at Amazon.com in the US. It is not yet recognized by the medical establishment as an anti-cancer drug, however, it many physicians are able to recommend its usage for reasons other than treating worms.Add mebendazole to the growing list of so-called ‘alternative’ cancer treatments which are affordable, effective, widely available, yet broadly ignored by the cancer industry.

Read more articles from Alex Pietrowski. About the Author

Alex Pietrowski is an artist and writer concerned with preserving good health and the basic freedom to enjoy a healthy lifestyle. He is a staff writer for WakingTimes.com and Offgrid Outpost, a provider of storable food and emergency kits. Alex is an avid student of Yoga and life.

Sources:

-http://viewzone.com/mebendazole.html
-https://en.wikipedia.org/wiki/Mebendazole
-http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096024/
-http://www.ncbi.nlm.nih.gov/pubmed/12479701
-http://neuro-oncology.oxfordjournals.org/content/early/2011/07/14/neuonc.nor077.full

A Promising New Drug Kills Pain Like Morphine—And It’s Not Addictive, Either

by Jordan E. Rosenfeld
Throw around the word “opioid”—a morphine-derived painkiller like heroin, Vicodin, or Oxycontin—and “epidemic” is likely to follow. The Centers for Disease Control estimates that U.S. deaths from opioid abuse are at a record high, with 78 fatalities occurring every day, a number that has quadrupled since 1999. A 2016 Kaiser Health survey found that nearly half of respondents reported knowing someone with an addiction to heroin, which in certain parts of the country is becoming a cheap, easily accessible alternative once the prescription runs out.

Congress has responded by authorizing $181 million in state grants for substance abuse treatment centers, while President Obama has made anti-addiction drugs more available. Yet the root cause remains largely unaddressed: People keep overdosing on opioids because they’re as incredibly effective—and dangerously addictive—as ever.

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But help appears to be on the way, thanks to scientists across four institutions—UC San Francisco, Stanford University, the University of North Carolina, and the Friedrich-Alexander University Erlangen-Nurnberg in Germany—who’ve developed a compound from scratch that kills pain just as effectively as opioids, though it has entirely different characteristics.
If you use opiates you get to kiss God. So your brain starts telling you to go do it again.

The four-year effort was funded by the U.S. National Institutes of Health. Rather than beginning as many studies on drug candidates do—by dissecting the molecular structure of a certain compound—the researchers began by looking at the brain. Specifically, the opioid receptor in the brain, which activates a signal in the dopamine circuit.

Brian Shoichet, PhD, a professor of pharmaceutical chemistry in UCSF’s School of Pharmacy and co-senior author on the paper, which was published last month in Nature, calls this “the happiness circuit, involved in a lot of types of addiction,” from nicotine to gambling and, yes, opioid addiction.

As described by Ivan Hodes of Alaska Commons:

The point of the signal is to make you remember that whatever you did felt good, so that you do it again the next time you have the opportunity. [When you take opioids, the] brain releases just gigantic amounts of dopamine, far more than are released by endorphins, and so you feel pleasure, euphoria, like you’ve never felt before (Lenny Bruce once described it as “like kissing God”).

Now your brain has learned something: If you use opiates you get to kiss God. So your brain starts telling you to go do it again, just begging you.

The key was to find a molecule that would bind well with that opioid receptor without affecting dopamine levels. Building on previous findings and using computational modeling, “We screened three trillion molecules, winnowed that down to twenty-three, and we went from there,” says Shoichet.

Eventually, the researchers were able to isolate a single molecule called PZM21.
There’s an American cultural phenomenon that goes with taking a pill, to have no symptoms at all and function at your highest level.

The chemical structure of this molecule is very different from opioids,” Shoichet says, and does not activate the dopamine circuit in mice, which the team tested for signs of addiction. Years later, those signs simply aren’t there. The mice didn’t experience a slowdown in breathing either, which is a major contributor to opioid-related deaths.

Like morphine, this molecule binds to the mu-opioid receptor,” Shoichet explains, but unlike morphine, PZM21 doesn’t activate the neural pathway that leads to side effects like depressed respiration and constipation.

The drug is a big step toward ending our national addiction to prescription narcotics, which likely kicked off in the late 1980s when a series of studies minimized the addictive nature of opioids right around the same time that organizations like the American Pain Society “campaigned to make pain what it called the ‘fifth vital sign’ that doctors should monitor, alongside blood pressure, temperature, heartbeat and breathing.”

Harold Jonas, PhD, LMHC, a Florida-based addiction counselor, and creator of an opioid recovery app called FlexDek MAT, believes the epidemic stems from what he sees as a uniquely American attitude, a “cultural phenomenon that goes with taking a pill, to have no symptoms at all and function at your highest level under the influence of different chemicals.”

PMZ21 is not a perfect painkiller, however, and it will be about a year or two before it goes into human clinical trials. While it relieves what Shoichet calls “conscious pain,” or the ongoing perception of pain, the drug does not affect “reflex pain,” which tells you to pull your hand away from a hot object before your brain actually registers your seared flesh. (Good news for the mice, at least: Placed on hot plates and dosed with PMZ21, they experienced as much pain relief as those on morphine without a dulled urge to jump off, according to Shoichet.)

Still, Shoichet says his team was “totally blown away by the results,” calling their discovery a “triumph of basic science.” Meanwhile, more progress is being made—another recent study published in the Nature journal Neuropsychopharmacology has found a brain mechanism that, if targeted by medication, could reduce one’s tolerance to morphine.

Source: health.good.is

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