Ankylosing Spondylitis

What causes ankylosing spondylitis?

The majority of people (90%) with AS have a gene called HLA-B27. The HLA-B27 gene appears only to increase the tendency of developing AS, while some factor(s), perhaps environmental, are necessary for the disease to become expressed. Not everyone with AS carries this gene; therefore, if your doctor tests you and you don’t have it you may still have AS.

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